For Members of the Action F2F or online attendance is by invitation only via the e-COST platform.
We are also pleased to open registration for external participants for the SENSCENCE2030 Conference & Workshop at the University of Coimbra, either in person (30 places) and online (50 places).
Please apply here.
Location
Hybrid Auditorium, Faculty of Medicine building (polo I), second floor, University of Coimbra, Rua Larga, 3004-504
Conference Programme | Tuesday 19th May 2026
Translating biological insights into strategies for promoting healthy ageing
08:30 – 09:00 Registration & Coffee
09:00 – 09:15 Welcome by the Chair of the Action
09:15 – 10:55 Recent Advancements on the Physio-Pathological Role of Cell Senescence, Part 1
Topic: From physiology to pathology
Session organized by Senescence2030 Working Group “Advancement of Knowledge on Cell Senescence and Aging”
Chair: Prof. Marco Demaria / Co-Chair Prof. Cleo Bishop
09:15 – 09:40 Bill Keyes (France). Uncovering fundamental drivers and phenotypes of cellular senescence
09:40 – 10:05 Han Li (France). Beneficial and detrimental senescence
10.05 –10.30 Mikolaj Ogrodnik (Austria). Senescence in tissue repair
10:30 – 10:55 Elsa Logarinho (Portugal). Genomic instability in aging – from mechanisms to interventions
10:55 – 11:25 Coffee Break
11:25 – 13:05 Biomarkers and Therapeutic Frontiers Part 1
Topic: Senescence in Neurological Aging
Session organized by Senescence2030 Working Group “From Knowledge on Senescence to the Impact on Age-Related Diseases”
Chair: Prof. Pasquale Maffia / Co-Chair YRI TBD
11:25 – 11:50 Evžen Amler (Czech Republic). Liquid Biopsy on Functionalized Glass for Biological Age Monitoring
11:50 – 12:15 Marziyya Mammadova (Azerbaijan). Clinical phenotypes of accelerated vascular and neurological ageing: real-world evidence from neurological practice
12:15 – 12:40 Carmela Matrone (Italy). The Contribution of Circulating Metabolites to Neuronal Aging
12:40 – 13:05 Barbara Zavan (Italy). Advances in Senescence Detection Within the Brain: The Exosome
13:05 – 14:15 Lunch
(please confirm your reservation for the lunch with the LO – payment will be onsite by card)
14:15 – 15:55 Recent Advancements on the Physio-Pathological Role of Cell Senescence, Part 2
Topic: Senescence and Cancer
Session organized by Senescence2030 Working Group “Advancement of Knowledge on Cell Senescence and Aging”
Chair: Prof. Marco Demaria/ Co-Chair Fabrizio d’Adda di Fagagna
14:15 – 14:40 Ann Wouters (Belgium). Therapy-induced senescence
14:40 – 15:05 Ignacio Palmero (Spain). Understanding heterogeneity in cellular senescence
15:05 – 15:30 Daniel Munoz-Espin (UK). Senescence in the Tumour Microenvironment and Therapeutic Strategies
15:30 – 16:30 Keynote Talk
Nathan LeBrasseur, Mayo Clinic (USA). Cellular Senescence and Skeletal Muscle Aging
16:30 – Guided tour of the library TBC
(please confirm with the LO your reservation for the tour – any payment will be onsite by credit card)
Conference Programme | Wednesday 20th May 2026
09:00 – 10:40 Biomarkers and Therapeutic Frontiers, Part 2
Topic: Senescence heterogeneity and implications
Session organized by Senescence2030 Working Group “From Knowledge on Senescence to the Impact on Age-Related Diseases”
Chair: Prof. Pasquale Maffia/Co-Chair Prof. Ulf Smith
09:00 – 9:25 Johannes Grillari (Austria). A novel senolytic compound targeting arachidonic acid conversion improves outcome of stroke and chronic kidney disease in pre-clinical models
9:25 – 9:50 Francesco Nicoli (Italy). Metabolic and viral imprints on the aging immune system: intrinsic and extrinsic determinants of vaccine and antiviral responses
9:50 – 10: 15 Luca Pangrazzi (Austria). Defining and targeting cellular senescence in immune cells
10:15 – 10:40 Gregory Alexander Raciti (Italy). Innovative tools for predicting incident cardiovascular events in patients with Type 2 Diabetes
10:40 – 11:00 Jasper Iske (Germany). Senotherapies for Solid Organ Transplantation
11:00 – 11:25 Coffee Break
11:25 – 12:25 Keynote Talk
Mahmoud Abdellatif (Austria). Senescence-autophagy crosstalk in cardiovascular aging and related disease
12:25 – 12:50 Vincenzo Atella (Italy). Socio-economic determinants of aging
A talk organized by Senescence2030 Working Group
The Societal Impact of Cell Senescence Research and Related Policy
12:50 – 13:00 Closure of the Session
13:00 – 15:00 Extended Coffee Break/ Poster session by fellows in the Training School to immediately foster connections and stimulate discussion
Workshop Programme – Wednesday 20th May 2026
Translating biological insights into strategies for promoting healthy ageing
15:00 – 17:30 Industry–Academia Workshop on Innovation in Cell Senescence Detection and Treatments
The workshop specifically targets the pharmaceutical and biotech industries
Topic: Industry and Regulatory
GMP, innovation pipeline, scaling, ethics, and regulatory frameworks
Expected Outputs: New collaborative agreements, Technology transfer opportunities, Stakeholder feedback on applicability of research, Preclinical pipelines aligned with regulatory and industry needs, Proposed guidelines on senescence research methodologies (TS)
Coordinator: Prof. Marco Demaria
15:00 – 15:10 Introduction of round tables participants: Industry representatives (biotech, pharma, AI/biomanufacturing)
Lorna Harries, Professor in Molecular Genetics, University of Exeter Medical School
Alberto Vitari, Rubedolife
Robin Mansukhani, Deciduoustx
Benjamin Lecalve, Starkagetx
Helena Baiao, National Coordinator of Portugal, European Infrastructure for Translational Medicine (EATRIS)
15:10 –15:30 Talk from the Action members
Ioannis P. Trougakos (Greece). Recent Developments in Senolytic and Senomorphic Therapies
15:30 – 16:00 Round Table 1
Participants: TBD
16:00 – 16:20 Coffee Break
16:20 – 17:20 Companies Pitch
17:20 – 17:45 Round Table 2
Participants: TBD
17:45 – 18:30 Closing the workshop