WG1
Advancement of Knowledge on Cell Senescence and Aging
SENESCENCE2030 will produce an interdisciplinary collaborative effort to identify knowledge gaps, emerging trends, and potential areas for further exploration of cell senescence in relation to human aging.
WG1 Topics
- Topic 1: Omics, biomarkers and bioinformatics
- Topic 2: Ex vivo/in vivo models
- Topic 3: Physiological vs Pathological senescence
- Topic 4: Novel therapeutic interventions

WG2
From Knowledge on Senescence to the Impact on Age-Related Diseases
Collaborations will be promoted between individual laboratories participating in SENESCENCE2030 in adopting omic approaches (including genomics, transcriptomics, proteomics, epigenomics, microbiomics and single-cell analytic tools).
WG2 Topics
- Topic 1: Cardiometabolic Diseases
- Topic 2: Immunology & Immunometabolism
- Topic 3: Neuromuscular & Neuroscience
- Topic 4: Cancer
- Topic 5: Frailty & Aging
- Topic 6: Pharmacology & Therapeutics

WG3
The Societal Impact of Cell Senescence Research and Related Policies
Exploring Novel Opportunities for Healthy Aging: SENESCENCE2030 will produce timely,
authoritative reviews of interventions targeting cellular senescence at different times through human life.

WG4
Dissemination and Public Engagement
This working group focuses on sharing research findings, fostering collaboration, and engaging with the public to enhance awareness and understanding of scientific advancements. Through publications, conferences, outreach activities, and digital platforms, we aim to bridge the gap between research and society, ensuring knowledge is accessible and impactful.
WG4 Topics
- Topic 1: Website Content
- Topic 2: Social Media Presence
- Topic 3: Young Researcher Opportunities
- Topic 4: Stakeholder Engagement
- Topic 5: Public Engagement

WG4 Leader
Mariana Pavel-Tanasa
Romania